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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED13L All Species: 21.52
Human Site: T867 Identified Species: 39.44
UniProt: Q71F56 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q71F56 NP_056150.1 2210 242602 T867 D L Q R M F P T P P S L E Q H
Chimpanzee Pan troglodytes XP_001138050 2188 240763 M847 S T A D L H K M Y P T P P S L
Rhesus Macaque Macaca mulatta XP_001112106 2210 242628 T867 D L Q R M F P T P P S L E Q H
Dog Lupus familis XP_534693 2280 250152 T936 D L Q R M F P T P P S L E Q H
Cat Felis silvestris
Mouse Mus musculus Q6JPI3 2207 241740 T862 D L Q R M F P T P P S L E Q H
Rat Rattus norvegicus NP_001101807 1374 149708 V73 E S P V V S M V P T H L T E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509907 2170 238695 K829 I S T A D L H K M Y P T P P S
Chicken Gallus gallus XP_415317 2195 241321 T844 D L Q R M F P T P P S L E Q H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2VCZ5 2102 230974 L782 F N S D E D D L T Q P G S R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KTX8 2618 280005 T1062 C Q T D V V M T D L S V D T T
Honey Bee Apis mellifera XP_393643 1982 216109 D681 I F D N S D P D T S S D E T N
Nematode Worm Caenorhab. elegans Q93442 2862 325119 S1217 P M A S I F Q S P T M P P P H
Sea Urchin Strong. purpuratus XP_001203054 1127 123639
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.7 99.2 93.3 N.A. 92.4 57.7 N.A. 53.5 86.4 N.A. 50.2 N.A. 24.8 33.9 21.2 25.6
Protein Similarity: 100 69.3 99.6 94.7 N.A. 95.7 59.9 N.A. 69.7 92.5 N.A. 66.4 N.A. 41.5 50.5 38.5 35.1
P-Site Identity: 100 6.6 100 100 N.A. 100 13.3 N.A. 0 100 N.A. 0 N.A. 13.3 20 20 0
P-Site Similarity: 100 20 100 100 N.A. 100 33.3 N.A. 0 100 N.A. 6.6 N.A. 33.3 26.6 40 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 8 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 39 0 8 24 8 16 8 8 8 0 0 8 8 0 0 % D
% Glu: 8 0 0 0 8 0 0 0 0 0 0 0 47 8 0 % E
% Phe: 8 8 0 0 0 47 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 8 8 0 0 0 8 0 0 0 47 % H
% Ile: 16 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % K
% Leu: 0 39 0 0 8 8 0 8 0 8 0 47 0 0 8 % L
% Met: 0 8 0 0 39 0 16 8 8 0 8 0 0 0 0 % M
% Asn: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 8 0 8 0 0 0 47 0 54 47 16 16 24 16 0 % P
% Gln: 0 8 39 0 0 0 8 0 0 8 0 0 0 39 0 % Q
% Arg: 0 0 0 39 0 0 0 0 0 0 0 0 0 8 8 % R
% Ser: 8 16 8 8 8 8 0 8 0 8 54 0 8 8 8 % S
% Thr: 0 8 16 0 0 0 0 47 16 16 8 8 8 16 8 % T
% Val: 0 0 0 8 16 8 0 8 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _